New Hampshire Man Receives Human kidney After Genetically Modified Pig kidney Was Rejected
USA: A year after receiving one of the worldβs first genetically modified pig kidneys, a New Hampshire man identified as Andrews has now undergone a human kidney transplant and is recovering. Andrews lived with the pig kidney for 271 days before his immune system ultimately rejected that organ. On January 12 a nearβperfect human kidney match was identified, and he went into transplant surgery the following day.
The case has captured attention because it bridges two stages of transplant innovation: experimental xenotransplantation using a geneβedited pig organ, followed by a conventional human kidney transplantation. The initial pig kidney implantation extended Andrewsβs time off the waiting list and provided crucial clinical information about crossβspecies organ function and immune response. Its eventual failure underscored the persistent challenges of immune compatibility and longβterm survival in xenotransplantation, while also clearing the way for a standard human donor organ to be procured and placed.
Surgeons moved swiftly when the compatible human organ became available, performing the operation immediately after the match was confirmed. Andrewsβs recovery is being monitored as clinicians evaluate both the performance of the human graft and what lessons the pig kidney trial offered about immunosuppression, infection risk, and organ preservation. The sequence β experimental pig kidney, months of function, rejection, then rapid human transplantation β highlights both the promise and limits of current strategies to expand the donor pool.
Beyond one patientβs outcome, the episode may influence protocols for future experimental transplants and the management of patients who receive them. Medical teams and transplant programs are closely following Andrewsβs progress as part of broader efforts to refine techniques that could shorten wait times and improve longβterm outcomes for people needing lifeβsaving kidney transplantation.
Video originally published on 2026-01-16 21:40:55
