Mount Sinai Surgeons Perform First Human Tracheal Transplant

A team of Mount Sinai NY surgeons has performed the first-ever successful human trachea transplant—an achievement that has the potential to become a viable life-saving treatment for thousands of patients around the world who have tracheal birth defects, untreatable airway diseases, burns, tumors, or severe tracheal damage from intubation – including those hospitalized with COVID-19 and placed on a ventilator. Prior to this historic transplant, there has been no long-term treatment for this patient population, and thousands for adults and children die each year as a result.

The 18-hour tracheal transplant procedure, which took place January 13, 2021, was led by surgeon-scientist, Eric Genden, MD, MHCA, FACS, the Isidore Friesner Professor and Chair of Otolaryngology—Head and Neck Surgery for the Mount Sinai Health System and Professor of Neurosurgery and Immunology at the Icahn School of Medicine at Mount Sinai. The complex surgery involved a team of more than 50 specialists including surgeons, nurses, anesthesiologists, and residents,

In this video, Dr. Genden and Sander S. Florman, MD, The Charles Miller, MD Professor of Surgery and Director of Recanati/Miller Transplantation Institute at Mount Sinai describe the process leading up to and during the procedure.

To make an appointment, call 212-241-9410 or visit

Dr. Eric Genden Profile:

Dr. Sander S. Florman Profile:


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