Lung Transplant Recipient Defies All Odds



Meara Schmidt, 28, almost died a few weeks ago. Lying in her hospital bed at UCLA, the seriously ill cystic fibrosis patient felt herself slipping away and her life flashing by. But then the image of her husband appeared, and she knew she was not ready to go.

A series of dramatic medical ups and downs had Schmidt “on” the transplant list, then “off” the list. At one point, her right lung stopped functioning, her left lung only partially worked and a machine that provided oxygen had to be dialed up to 100 percent.

Twice, when her tracheostomy and mechanical ventilation was insufficient to provide enough oxygen, she was put on a last-ditch life-support system called extra-corporeal membrane oxygenation, or ECMO, which took over her breathing function through a cannula surgically placed in her neck.

But she would not give up.

In fact, while on ECMO and attached to a tower of medicine lines and pumps, she was able to get up and walk. Traditionally, patients on ECMO are sedated and immobile, but a new innovative ambulatory ECMO approach has been shown to help certain patients gain strength and muscle mass in preparation for surgery. With this new “bridge” approach, Schmidt was not sedated but alert and able to walk, which helped keep her well enough for transplant surgery. She was also working hard to gain weight and fight off various disease-related infections.

But despite her determination, her condition was declining and time was running out.

“Meara’s tenaciousness and her sufficient recovery from ECMO convinced us that we should still pursue transplantation,” said Dr. David Ross, a professor of pulmonology and medical director of the UCLA Lung Transplant Program. “I seldom witness ‘miracles of medicine,’ but shortly after she was listed again on the active transplant list, the perfect pair of donor lungs became available.”

Learn more about Meara’s Story at http://ucla.in/OaRN3m.

Learn more about transplantation at UCLA at transplants.ucla.edu

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