Researchers at the University of Saskatchewan have developed a new dialysis membrane that could improve treatment for patients with kidney failure. Dialysis machines are used to filter toxins and waste products from the blood when the kidneys are unable to do so effectively. However, negative reactions between dialysis membranes and the patient’s blood can lead to complications such as blood clots and infections. The new membrane developed by the researchers maintains a reduction in blood clotting while also having a neutral surface that is biocompatible, which should lead to improved outcomes for patients. It also has a more stable hydration layer, making it more efficient than current commercial membranes.
The researchers used the Canadian Light Source (CLS) at the University of Saskatchewan to analyze and develop their membrane. The CLS’s BMIT beamline allowed the team to monitor the flow in each layer of the membrane in real time, providing valuable insights into protein accumulation and membrane blockages. The team has filed a provisional patent for one of the top-performing membrane materials they developed and continues to test and refine the membrane to ensure its safety and effectiveness. The goal is to improve the quality of life for patients on dialysis by reducing physical and psychological symptoms associated with the treatment.